Which antiseptic is commonly used for skin preparation before venipuncture?

The choice of 70% isopropyl alcohol as the antiseptic for skin preparation before venipuncture is grounded in its effectiveness in reducing skin flora, which helps to minimize the risk of infection during the procedure. This concentration is optimal because it contains enough alcohol to kill bacteria while also allowing for some evaporation time, which enhances its antiseptic properties.

Using alcohol swabs may not provide the same level of disinfection as the 70% solution when applied with the appropriate technique, as swabbing may lead to a less effective application. Chlorhexidine is another valid antiseptic that some facilities prefer due to its longer-lasting antibacterial effects, especially for high-risk patients or procedures. Hydrogen peroxide, while an antiseptic, can irritate the skin and is generally not recommended for venipuncture as it may cause discomfort or a chemical reaction.

In the context of standard practice for venipuncture, 70% isopropyl alcohol remains a widely accepted choice due to its balance of efficacy and safety, making it suitable for most routine blood collection procedures.